Clinical, Genomic and Metagenomic Characterization of Oral Tongue Squamous Cell Carcinoma in Patients Who Do Not Smoke

BACKGROUND: Evidence suggests the incidence of oral tongue squamous cell carcinoma is increasing in young patients, many who have no history of tobacco use. METHODS: We clinically reviewed 89 oral tongue cancer patients. Exomic sequencing of tumor DNA from 6 non-smokers was performed and compared to...

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Publicado no:Head Neck
Main Authors: Li, Ryan, Faden, Daniel L., Fakhry, Carole, Langelier, Chaz, Jiao, Yuchen, Wang, Yuxuan, Wilkerson, Matthew D., Pedamallu, Chandra Sekhar, Old, Matthew, Lang, James, Loyo, Myriam, Ahn, Sun Mi, Tan, Marietta, Gooi, Zhen, Chan, Jason, Richmon, Jeremy, Wood, Laura D., Hruban, Ralph H., Bishop, Justin, Westra, William H., Chung, Christine H., Califano, Joseph, Gourin, Christine G., Bettegowda, Chetan, Meyerson, Matthew, Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert, DeRisi, Joseph L., Koch, Wayne M., Agrawal, Nishant
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272912/
https://ncbi.nlm.nih.gov/pubmed/24954188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hed.23807
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