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Redesigning Recombinase Specificity for Safe Harbor Sites in the Human Genome
Site-specific recombinases (SSRs) are valuable tools for genetic engineering due to their ability to manipulate DNA in a highly specific manner. Engineered zinc-finger and TAL effector recombinases, in particular, are two classes of SSRs composed of custom-designed DNA-binding domains fused to a cat...
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| Publicado no: | PLoS One |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4587366/ https://ncbi.nlm.nih.gov/pubmed/26414179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139123 |
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