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Beyond genomics: critical evaluation of cell line utility for ovarian cancer research
OBJECTIVE: Comparisons of The Cancer Genome Atlas (TCGA) with high grade serous ovarian cancer (HGSOC) cell lines used in research reveal that many common experimental models lack defining genomic characteristics seen in patient tumors. As cell lines exist with higher genomic fidelity to TCGA, this...
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| Publicado no: | Gynecol Oncol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4587360/ https://ncbi.nlm.nih.gov/pubmed/26321251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2015.08.017 |
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