Epigenetic remodeling regulates transcriptional changes between ovarian cancer and benign precursors

Regulation of lineage-restricted transcription factors has been shown to influence malignant transformation in several types of cancer. Whether similar mechanisms are involved in ovarian cancer pathogenesis is unknown. PAX8 is a nuclear transcription factor that controls the embryologic development...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Elias, Kevin M., Emori, Megan M., Westerling, Thomas, Long, Henry, Budina-Kolomets, Anna, Li, Fugen, MacDuffie, Emily, Davis, Michelle R., Holman, Alexander, Lawney, Brian, Freedman, Matthew L., Quackenbush, John, Brown, Myles, Drapkin, Ronny
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017158/
https://ncbi.nlm.nih.gov/pubmed/27617304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87988
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