Proteomic Analysis of ABCA1-Null Macrophages Reveals a Role for Stomatin-Like Protein-2 in Raft Composition and Toll-Like Receptor Signaling

Lipid raft membrane microdomains organize signaling by many prototypical receptors, including the Toll-like receptors (TLRs) of the innate immune system. Raft-localization of proteins is widely thought to be regulated by raft cholesterol levels, but this is largely on the basis of studies that have...

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Udgivet i:Mol Cell Proteomics
Main Authors: Chowdhury, Saiful M., Zhu, Xuewei, Aloor, Jim J., Azzam, Kathleen M., Gabor, Kristin A., Ge, William, Addo, Kezia A., Tomer, Kenneth B., Parks, John S., Fessler, Michael B.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2015
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587328/
https://ncbi.nlm.nih.gov/pubmed/25910759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M114.045179
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