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Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage

The minichromosome maintenance complex (MCM) proteins are required for processive DNA replication and are a target of S-phase checkpoints. The eukaryotic MCM complex consists of six proteins (MCM2–7) that form a heterohexameric ring with DNA helicase activity, which is loaded on chromatin to form th...

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Publié dans:Mol Cell Proteomics
Auteurs principaux: Drissi, Romain, Dubois, Marie-Line, Douziech, Mélanie, Boisvert, François-Michel
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587322/
https://ncbi.nlm.nih.gov/pubmed/25963833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.048991
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