Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage

The minichromosome maintenance complex (MCM) proteins are required for processive DNA replication and are a target of S-phase checkpoints. The eukaryotic MCM complex consists of six proteins (MCM2–7) that form a heterohexameric ring with DNA helicase activity, which is loaded on chromatin to form th...

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Bibliographic Details
Published in:Mol Cell Proteomics
Main Authors: Drissi, Romain, Dubois, Marie-Line, Douziech, Mélanie, Boisvert, François-Michel
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2015
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587322/
https://ncbi.nlm.nih.gov/pubmed/25963833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.048991
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