Destabilization of the MiniChromosome Maintenance (MCM) complex modulates the cellular response to DNA double strand breaks

DNA replication during S phase involves thousands of replication forks that must be coordinated to ensure that every DNA section is replicated only once. The minichromosome maintenance proteins, MCM2 to MCM7, form a heteromeric DNA helicase required for both the initiation and elongation of DNA repl...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Drissi, Romain, Chauvin, Anaïs, McKenna, Alyson, Lévesque, Dominique, Blais-Brochu, Simon, Jean, Dominique, Boisvert, François-Michel
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300108/
https://ncbi.nlm.nih.gov/pubmed/30516086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1553336
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