In Vivo Downregulation of Innate and Adaptive Immune Responses in Corneal Allograft Rejection by HC-HA/PTX3 Complex Purified From Amniotic Membrane

PURPOSE. Heavy chain–hyaluronic acid (HC-HA)/PTX3 purified from human amniotic membrane (AM) was previously observed to suppress inflammatory responses in vitro. We now examine whether HC-HA/PTX3 is able to exert a similar effect in vivo, using murine models for keratitis and corneal allograft rejec...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: He, Hua, Tan, Yaohong, Duffort, Stephanie, Perez, Victor L., Tseng, Scheffer C. G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586971/
https://ncbi.nlm.nih.gov/pubmed/24519420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-13094
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