Constitutive Expression of Pentraxin 3 (PTX3) Protein by Human Amniotic Membrane Cells Leads to Formation of the Heavy Chain (HC)-Hyaluronan (HA)-PTX3 Complex

Heavy chain (HC)-hyaluronan (HA), a complex formed by the covalent linkage between HC1 from the inter-α-trypsin inhibitor (IαI) and HA, purified from the human amniotic membrane (AM), is responsible for the anti-inflammatory, antiscarring, and antiangiogenic actions of the AM. This HC-HA complex is...

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Hauptverfasser: Zhang, Suzhen, Zhu, Ying-Ting, Chen, Szu-Yu, He, Hua, Tseng, Scheffer C. G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Glycobiology and Extracellular Matrices
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036359/
https://ncbi.nlm.nih.gov/pubmed/24652286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.525287
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