Transgenic Expression of Osteoactivin/gpnmb Enhances Bone Formation in Vivo and Osteoprogenitor Differentiation ex Vivo

Initial identification of osteoactivin (OA)/glycoprotein non-melanoma clone B (gpnmb) was demonstrated in an osteopetrotic rat model, where OA expression was increased 3-fold in mutant bones, compared to normal. OA mRNA and protein expression increase during active bone regeneration post-fracture, a...

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Publicado no:J Cell Physiol
Main Authors: Frara, Nagat, Abdelmagid, Samir M., Sondag, Gregory R., Moussa, Fouad M., Yingling, Vanessa R., Owen, Thomas A., Popoff, Steven N., Barbe, Mary F., Safadi, Fayez F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586905/
https://ncbi.nlm.nih.gov/pubmed/25899717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25020
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