Mutation in Osteoactivin Decreases Bone Formation in Vivo and Osteoblast Differentiation in Vitro

We have previously identified osteoactivin (OA), encoded by Gpnmb, as an osteogenic factor that stimulates osteoblast differentiation in vitro. To elucidate the importance of OA in osteogenesis, we characterized the skeletal phenotype of a mouse model, DBA/2J (D2J) with a loss-of-function mutation i...

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Bibliographische Detailangaben
Hauptverfasser: Abdelmagid, Samir M., Belcher, Joyce Y., Moussa, Fouad M., Lababidi, Suzanne L., Sondag, Gregory R., Novak, Kimberly M., Sanyurah, Afif S., Frara, Nagat A., Razmpour, Roshanak, Del Carpio-Cano, Fabiola E., Safadi, Fayez F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2014
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Regular Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936333/
https://ncbi.nlm.nih.gov/pubmed/24462663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.11.031
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