Osteoactivin inhibition of osteoclastogenesis is mediated through CD44-ERK signaling

Osteoactivin is a heavily glycosylated protein shown to have a role in bone remodeling. Previous studies from our lab have shown that mutation in Osteoactivin enhances osteoclast differentiation but inhibits their function. To date, a classical receptor and a signaling pathway for Osteoactivin-media...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Sondag, Gregory R, Mbimba, Thomas S, Moussa, Fouad M, Novak, Kimberly, Yu, Bing, Jaber, Fatima A, Abdelmagid, Samir M, Geldenhuys, Werner J, Safadi, Fayez F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050297/
https://ncbi.nlm.nih.gov/pubmed/27585719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2016.78
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