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Uniform and accurate single-cell sequencing based on emulsion whole-genome amplification

Whole-genome amplification (WGA) for next-generation sequencing has seen wide applications in biology and medicine when characterization of the genome of a single cell is required. High uniformity and fidelity of WGA is needed to accurately determine genomic variations, such as copy number variation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Fu, Yusi, Li, Chunmei, Lu, Sijia, Zhou, Wenxiong, Tang, Fuchou, Xie, X. Sunney, Huang, Yanyi
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586872/
https://ncbi.nlm.nih.gov/pubmed/26340991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1513988112
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