NMR structure and dynamics of the agonist dynorphin peptide bound to the human kappa opioid receptor

The structure of the dynorphin (1–13) peptide (dynorphin) bound to the human kappa opioid receptor (KOR) has been determined by liquid-state NMR spectroscopy. (1)H and (15)N chemical shift variations indicated that free and bound peptide is in fast exchange in solutions containing 1 mM dynorphin and...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: O’Connor, Casey, White, Kate L., Doncescu, Nathalie, Didenko, Tatiana, Roth, Bryan L., Czaplicki, Georges, Stevens, Raymond C., Wüthrich, Kurt, Milon, Alain
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2015
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586840/
https://ncbi.nlm.nih.gov/pubmed/26372966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510117112
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