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NMR structure and dynamics of the agonist dynorphin peptide bound to the human kappa opioid receptor
The structure of the dynorphin (1–13) peptide (dynorphin) bound to the human kappa opioid receptor (KOR) has been determined by liquid-state NMR spectroscopy. (1)H and (15)N chemical shift variations indicated that free and bound peptide is in fast exchange in solutions containing 1 mM dynorphin and...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4586840/ https://ncbi.nlm.nih.gov/pubmed/26372966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510117112 |
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