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Integrins activate trimeric G proteins via the nonreceptor protein GIV/Girdin

Signal transduction via integrins and G protein–coupled receptors is critical to control cell behavior. These two receptor classes have been traditionally believed to trigger distinct and independent signaling cascades in response to extracellular cues. Here, we report a novel mechanism of integrin...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Leyme, Anthony, Marivin, Arthur, Perez-Gutierrez, Lorena, Nguyen, Lien T., Garcia-Marcos, Mikel
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586755/
https://ncbi.nlm.nih.gov/pubmed/26391662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201506041
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