Integrins activate trimeric G proteins via the nonreceptor protein GIV/Girdin

Signal transduction via integrins and G protein–coupled receptors is critical to control cell behavior. These two receptor classes have been traditionally believed to trigger distinct and independent signaling cascades in response to extracellular cues. Here, we report a novel mechanism of integrin...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Leyme, Anthony, Marivin, Arthur, Perez-Gutierrez, Lorena, Nguyen, Lien T., Garcia-Marcos, Mikel
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586755/
https://ncbi.nlm.nih.gov/pubmed/26391662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201506041
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