ATP8B1-mediated spatial organization of Cdc42 signaling maintains singularity during enterocyte polarization

During yeast cell polarization localization of the small GTPase, cell division control protein 42 homologue (Cdc42) is clustered to ensure the formation of a single bud. Here we show that the disease-associated flippase ATPase class I type 8b member 1 (ATP8B1) enables Cdc42 clustering during enteroc...

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Détails bibliographiques
Publié dans:J Cell Biol
Auteurs principaux: Bruurs, Lucas J.M., Donker, Lisa, Zwakenberg, Susan, Zwartkruis, Fried J., Begthel, Harry, Knisely, A.S., Posthuma, George, van de Graaf, Stan F.J., Paulusma, Coen C., Bos, Johannes L.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2015
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586737/
https://ncbi.nlm.nih.gov/pubmed/26416959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201505118
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