ATP8B1-mediated spatial organization of Cdc42 signaling maintains singularity during enterocyte polarization

During yeast cell polarization localization of the small GTPase, cell division control protein 42 homologue (Cdc42) is clustered to ensure the formation of a single bud. Here we show that the disease-associated flippase ATPase class I type 8b member 1 (ATP8B1) enables Cdc42 clustering during enteroc...

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Veröffentlicht in:J Cell Biol
Hauptverfasser: Bruurs, Lucas J.M., Donker, Lisa, Zwakenberg, Susan, Zwartkruis, Fried J., Begthel, Harry, Knisely, A.S., Posthuma, George, van de Graaf, Stan F.J., Paulusma, Coen C., Bos, Johannes L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2015
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586737/
https://ncbi.nlm.nih.gov/pubmed/26416959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201505118
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