Diffusion of myosin light chain kinase on actin: A mechanism to enhance myosin phosphorylation rates in smooth muscle

Smooth muscle myosin (SMM) light chain kinase (MLCK) phosphorylates SMM, thereby activating the ATPase activity required for muscle contraction. The abundance of active MLCK, which is tightly associated with the contractile apparatus, is low relative to that of SMM. SMM phosphorylation is rapid desp...

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Dettagli Bibliografici
Pubblicato in:J Gen Physiol
Autori principali: Hong, Feng, Brizendine, Richard K., Carter, Michael S., Alcala, Diego B., Brown, Avery E., Chattin, Amy M., Haldeman, Brian D., Walsh, Michael P., Facemyer, Kevin C., Baker, Josh E., Cremo, Christine R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2015
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586593/
https://ncbi.nlm.nih.gov/pubmed/26415568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201511483
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