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Modification of Interface between Regulatory and Essential Light Chains Hampers Phosphorylation-dependent Activation of Smooth Muscle Myosin

We examined the regulatory importance of interactions between regulatory light chain (RLC), essential light chain (ELC), and adjacent heavy chain (HC) in the regulatory domain of smooth muscle heavy meromyosin. After mutating the HC, RLC, and/or ELC to disrupt their predicted interactions (using sca...

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מידע ביבליוגרפי
Main Authors: Ni, Shaowei, Hong, Feng, Haldeman, Brian D., Baker, Josh E., Facemyer, Kevin C., Cremo, Christine R.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381165/
https://ncbi.nlm.nih.gov/pubmed/22549781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.343491
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