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PTBP1 and PTBP2 impaired autoregulation of SRSF3 in cancer cells

Splicing factors are key players in the regulation of alternative splicing of pre-mRNAs. Overexpression of splicing factors, including SRSF3, has been strongly linked with oncogenesis. However, the mechanisms behind their overexpression remain largely unclear. Autoregulation is a common mechanism to...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Guo, Jihua, Jia, Jun, Jia, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586487/
https://ncbi.nlm.nih.gov/pubmed/26416554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14548
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