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PTBP1 and PTBP2 repress nonconserved cryptic exons

The fidelity of RNA splicing is maintained by a network of factors, but the molecular mechanisms that govern this process have yet to be fully elucidated. We previously found that TDP-43, an RNA-binding protein implicated in neurodegenerative disease, utilizes UG microsatellites to repress nonconser...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Ling, Jonathan P., Chhabra, Resham, Merran, Jonathan D., Schaughency, Paul M., Wheelan, Sarah J., Corden, Jeffry L., Wong, Philip C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082185/
https://ncbi.nlm.nih.gov/pubmed/27681424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.08.071
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