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The First Crystal Structure of the UP1 Domain of hnRNP A1 bound to RNA Reveals a New Look for an Old RNA Binding Protein

The hnRNP A1 protein is a multifunctional RNA binding protein implicated in a wide range of biological functions. Mechanisms and putative hnRNP A1-RNA interactions have been inferred primarily from the crystal structure of its UP1 domain bound to ssDNA. RNA stem loops represent an important class of...

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Библиографические подробности
Опубликовано в: :J Mol Biol
Главные авторы: Morgan, Christopher E., Meagher, Jennifer L., Levengood, Jeffrey D., Delproposto, James, Rollins, Carrie, Stuckey, Jeanne A., Tolbert, Blanton S.
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586317/
https://ncbi.nlm.nih.gov/pubmed/26003924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.05.009
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