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Repair of persistent strand breaks in the mitochondrial genome

Oxidative DNA damage has been attributed to increased cancer incidence and premature aging phenotypes. Reactive oxygen species (ROS) are unavoidable byproducts of oxidative phosphorylation and are the major contributors of endogenous oxidative damage. To prevent the negative effects of ROS, cells ha...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mech Ageing Dev
Main Authors: Sykora, Peter, Wilson, David M., Bohr, Vilhelm A.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586262/
https://ncbi.nlm.nih.gov/pubmed/22138376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2011.11.003
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