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Repair of persistent strand breaks in the mitochondrial genome
Oxidative DNA damage has been attributed to increased cancer incidence and premature aging phenotypes. Reactive oxygen species (ROS) are unavoidable byproducts of oxidative phosphorylation and are the major contributors of endogenous oxidative damage. To prevent the negative effects of ROS, cells ha...
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| Publicado no: | Mech Ageing Dev |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4586262/ https://ncbi.nlm.nih.gov/pubmed/22138376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2011.11.003 |
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