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Repair of persistent strand breaks in the mitochondrial genome

Oxidative DNA damage has been attributed to increased cancer incidence and premature aging phenotypes. Reactive oxygen species (ROS) are unavoidable byproducts of oxidative phosphorylation and are the major contributors of endogenous oxidative damage. To prevent the negative effects of ROS, cells ha...

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書目詳細資料
發表在:Mech Ageing Dev
Main Authors: Sykora, Peter, Wilson, David M., Bohr, Vilhelm A.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586262/
https://ncbi.nlm.nih.gov/pubmed/22138376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2011.11.003
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