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Age and gender effects on DNA strand break repair in peripheral blood mononuclear cells

Exogenous and endogenous damage to DNA is constantly challenging the stability of our genome. This DNA damage increase the frequency of errors in DNA replication, thus causing point mutations or chromosomal rearrangements and has been implicated in aging, cancer, and neurodegenerative diseases. Ther...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Garm, Christian, Moreno-Villanueva, Maria, Bürkle, Alexander, Petersen, Inge, Bohr, Vilhelm A., Christensen, Kaare, Stevnsner, Tinna
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586247/
https://ncbi.nlm.nih.gov/pubmed/23088435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12019
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