In Vitro Fluorogenic Real-time Assay of the Repair of Oxidative DNA Damage

The repair of oxidative damage to DNA is essential to avoidance of mutations that lead to cancer. Oxidized DNA bases, such as 8-oxoguanine, are a chief source of these mutations, and the enzyme 8-oxoguanine glycosylase 1 (OGG1) is the chief human enzyme that excises 8-oxoguanine from DNA. The activi...

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Pubblicato in:Chembiochem
Autori principali: Edwards, Sarah K., Ono, Toshikazu, Wang, Shenliang, Jiang, Wei, Franzini, Raphael M., Jung, Jong Wha, Chan, Ke Min, Kool, Eric T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586133/
https://ncbi.nlm.nih.gov/pubmed/26073452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201500184
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