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Monitoring eukaryotic and bacterial UDG repair activity with DNA-multifluorophore sensors
We report the development of simple fluorogenic probes that report on the activity of both bacterial and mammalian uracil–DNA glycosylase (UDG) enzymes. The probes are built from short, modified single-stranded oligonucleotides containing natural and unnatural bases. The combination of multiple fluo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3695528/ https://ncbi.nlm.nih.gov/pubmed/23644286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt309 |
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