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Templated Chemistry for Monitoring Damage and Repair Directly in Duplex DNA()
We report the fluorogenic detection of the product of base excision repair (an abasic site) in a specific sequence of duplex DNA. This is achieved by DNA-templated chemistry, employing triple helix-forming probes that contain unnatural nucleobases designed to selectively recognize the site of a miss...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3417126/ https://ncbi.nlm.nih.gov/pubmed/22782065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2cc34060g |
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