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Metabolism and function of hepatitis B virus cccDNA: Implications for the development of cccDNA-targeting antiviral therapeutics

Persistent hepatitis B virus (HBV) infection relies on the stable maintenance and proper functioning of a nuclear episomal form of the viral genome called covalently closed circular (ccc) DNA. One of the major reasons for the failure of currently available antiviral therapeutics to achieve a cure of...

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Bibliografiske detaljer
Udgivet i:Antiviral Res
Main Authors: Guo, Ju-Tao, Guo, Haitao
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586118/
https://ncbi.nlm.nih.gov/pubmed/26272257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2015.08.005
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