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Targeting Viral cccDNA for Cure of Chronic Hepatitis B

PURPOSE OF REVIEW: Chronic hepatitis B (CHB), caused by hepatitis B virus (HBV), is a major cause of advanced liver disease and hepatocellular carcinoma (HCC) worldwide. HBV replication is characterized by the synthesis of covalently closed circular (ccc) DNA which is not targeted by antiviral nucle...

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Detalhes bibliográficos
Publicado no:Curr Hepatol Rep
Main Authors: Ligat, Gaëtan, Goto, Kaku, Verrier, Eloi, Baumert, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613435/
https://ncbi.nlm.nih.gov/pubmed/36034467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11901-020-00534-w
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