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Targeting Viral cccDNA for Cure of Chronic Hepatitis B

PURPOSE OF REVIEW: Chronic hepatitis B (CHB), caused by hepatitis B virus (HBV), is a major cause of advanced liver disease and hepatocellular carcinoma (HCC) worldwide. HBV replication is characterized by the synthesis of covalently closed circular (ccc) DNA which is not targeted by antiviral nucle...

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Podrobná bibliografie
Vydáno v:Curr Hepatol Rep
Hlavní autoři: Ligat, Gaëtan, Goto, Kaku, Verrier, Eloi, Baumert, Thomas F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613435/
https://ncbi.nlm.nih.gov/pubmed/36034467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11901-020-00534-w
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