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Targeting Viral cccDNA for Cure of Chronic Hepatitis B

PURPOSE OF REVIEW: Chronic hepatitis B (CHB), caused by hepatitis B virus (HBV), is a major cause of advanced liver disease and hepatocellular carcinoma (HCC) worldwide. HBV replication is characterized by the synthesis of covalently closed circular (ccc) DNA which is not targeted by antiviral nucle...

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Bibliografiska uppgifter
I publikationen:Curr Hepatol Rep
Huvudupphovsmän: Ligat, Gaëtan, Goto, Kaku, Verrier, Eloi, Baumert, Thomas F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613435/
https://ncbi.nlm.nih.gov/pubmed/36034467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11901-020-00534-w
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