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Targeting Viral cccDNA for Cure of Chronic Hepatitis B

PURPOSE OF REVIEW: Chronic hepatitis B (CHB), caused by hepatitis B virus (HBV), is a major cause of advanced liver disease and hepatocellular carcinoma (HCC) worldwide. HBV replication is characterized by the synthesis of covalently closed circular (ccc) DNA which is not targeted by antiviral nucle...

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Bibliografske podrobnosti
izdano v:Curr Hepatol Rep
Main Authors: Ligat, Gaëtan, Goto, Kaku, Verrier, Eloi, Baumert, Thomas F.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613435/
https://ncbi.nlm.nih.gov/pubmed/36034467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11901-020-00534-w
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