Targeting RNA for degradation with a (2'-5')oligoadenylate-antisense chimera.

Antisense oligonucleotides hold considerable promise both as research tools for inhibiting gene expression and as agents for the treatment of a myriad of human diseases. However, targeted destruction of RNA has been difficult to achieve in a versatile, efficient, and reliable manner. We have develop...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Torrence, P F, Maitra, R K, Lesiak, K, Khamnei, S, Zhou, A, Silverman, R H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45860/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7679499/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.4.1300
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