HMGA1 overexpression in adipose tissue impairs adipogenesis and prevents diet-induced obesity and insulin resistance

High-Mobility-Group-A1 (HMGA1) proteins are non-histone proteins that regulate chromatin structure and gene expression during embryogenesis, tumourigenesis and immune responses. In vitro studies suggest that HMGA1 proteins may be required to regulate adipogenesis. To examine the role of HMGA1 in viv...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Arce-Cerezo, Altamira, García, Miquel, Rodríguez-Nuevo, Aida, Crosa-Bonell, Mireia, Enguix, Natalia, Peró, Albert, Muñoz, Sergio, Roca, Carles, Ramos, David, Franckhauser, Sylvie, Elias, Ivet, Ferre, Tura, Pujol, Anna, Ruberte, Jesús, Villena, Josep A., Bosch, Fàtima, Riu, Efrén
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585969/
https://ncbi.nlm.nih.gov/pubmed/26411793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14487
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