HMGA1 overexpression in adipose tissue impairs adipogenesis and prevents diet-induced obesity and insulin resistance

High-Mobility-Group-A1 (HMGA1) proteins are non-histone proteins that regulate chromatin structure and gene expression during embryogenesis, tumourigenesis and immune responses. In vitro studies suggest that HMGA1 proteins may be required to regulate adipogenesis. To examine the role of HMGA1 in viv...

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Publicado en:Sci Rep
Main Authors: Arce-Cerezo, Altamira, García, Miquel, Rodríguez-Nuevo, Aida, Crosa-Bonell, Mireia, Enguix, Natalia, Peró, Albert, Muñoz, Sergio, Roca, Carles, Ramos, David, Franckhauser, Sylvie, Elias, Ivet, Ferre, Tura, Pujol, Anna, Ruberte, Jesús, Villena, Josep A., Bosch, Fàtima, Riu, Efrén
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585969/
https://ncbi.nlm.nih.gov/pubmed/26411793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14487
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