HMGA1 overexpression in adipose tissue impairs adipogenesis and prevents diet-induced obesity and insulin resistance

High-Mobility-Group-A1 (HMGA1) proteins are non-histone proteins that regulate chromatin structure and gene expression during embryogenesis, tumourigenesis and immune responses. In vitro studies suggest that HMGA1 proteins may be required to regulate adipogenesis. To examine the role of HMGA1 in viv...

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Vydáno v:Sci Rep
Hlavní autoři: Arce-Cerezo, Altamira, García, Miquel, Rodríguez-Nuevo, Aida, Crosa-Bonell, Mireia, Enguix, Natalia, Peró, Albert, Muñoz, Sergio, Roca, Carles, Ramos, David, Franckhauser, Sylvie, Elias, Ivet, Ferre, Tura, Pujol, Anna, Ruberte, Jesús, Villena, Josep A., Bosch, Fàtima, Riu, Efrén
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585969/
https://ncbi.nlm.nih.gov/pubmed/26411793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14487
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