Lipoproteins/peptides are sepsis-inducing toxins from bacteria that can be neutralized by synthetic anti-endotoxin peptides

Sepsis, a life-threatening syndrome with increasing incidence worldwide, is triggered by an overwhelming inflammation induced by microbial toxins released into the bloodstream during infection. A well-known sepsis-inducing factor is the membrane constituent of Gram-negative bacteria, lipopolysacchar...

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Udgivet i:Sci Rep
Main Authors: de Tejada, Guillermo Martinez, Heinbockel, Lena, Ferrer-Espada, Raquel, Heine, Holger, Alexander, Christian, Bárcena-Varela, Sergio, Goldmann, Torsten, Correa, Wilmar, Wiesmüller, Karl-Heinz, Gisch, Nicolas, Sánchez-Gómez, Susana, Fukuoka, Satoshi, Schürholz, Tobias, Gutsmann, Thomas, Brandenburg, Klaus
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585737/
https://ncbi.nlm.nih.gov/pubmed/26390973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14292
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