Calreticulin is required for development of the cumulus oocyte complex and female fertility

Calnexin (CANX) and calreticulin (CALR) chaperones mediate nascent glycoprotein folding in the endoplasmic reticulum. Here we report that these chaperones have distinct roles in male and female fertility. Canx null mice are growth retarded but fertile. Calr null mice die during embryonic development...

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Vydáno v:Sci Rep
Hlavní autoři: Tokuhiro, Keizo, Satouh, Yuhkoh, Nozawa, Kaori, Isotani, Ayako, Fujihara, Yoshitaka, Hirashima, Yumiko, Matsumura, Hiroyuki, Takumi, Kazuhiro, Miyano, Takashi, Okabe, Masaru, Benham, Adam M., Ikawa, Masahito
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585710/
https://ncbi.nlm.nih.gov/pubmed/26388295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14254
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