Calreticulin is required for development of the cumulus oocyte complex and female fertility

Calnexin (CANX) and calreticulin (CALR) chaperones mediate nascent glycoprotein folding in the endoplasmic reticulum. Here we report that these chaperones have distinct roles in male and female fertility. Canx null mice are growth retarded but fertile. Calr null mice die during embryonic development...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Tokuhiro, Keizo, Satouh, Yuhkoh, Nozawa, Kaori, Isotani, Ayako, Fujihara, Yoshitaka, Hirashima, Yumiko, Matsumura, Hiroyuki, Takumi, Kazuhiro, Miyano, Takashi, Okabe, Masaru, Benham, Adam M., Ikawa, Masahito
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585710/
https://ncbi.nlm.nih.gov/pubmed/26388295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14254
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