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Huntington’s disease—the sting in the tail

Huntington’s disease (HD) is a progressive neurodegenerative condition caused by the abnormal expansion of a polyglutamine tract in the N-terminus of the huntingtin protein. Over the last 20 years, HD pathogenesis has been explained by the generation of N-terminal fragments containing the polyglutam...

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Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: Jimenez-Sanchez, Maria, Rubinsztein, David C
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Ltd 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585458/
https://ncbi.nlm.nih.gov/pubmed/26224597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201592467
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