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Polyalanine and polyserine frameshift products in Huntington's disease
Codon reiteration disorders are caused by abnormal expansions of either polyglutamine or polyalanine tracts within the coding region of a protein. These mutations impair normal protein folding, resulting in aggregate formation in the affected tissues. Huntington's disease is the most common of...
में बचाया:
| मुख्य लेखकों: | , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
BMJ Group
2006
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2563184/ https://ncbi.nlm.nih.gov/pubmed/16801344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2006.044222 |
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