Pichia pastoris-expressed dengue 3 envelope-based virus-like particles elicit predominantly domain III-focused high titer neutralizing antibodies

Dengue poses a serious public health risk to nearly half the global population. It causes ~400 million infections annually and is considered to be one of the fastest spreading vector-borne diseases. Four distinct serotypes of dengue viruses (DENV-1, -2, -3, and -4) cause dengue disease, which may be...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Tripathi, Lav, Mani, Shailendra, Raut, Rajendra, Poddar, Ankur, Tyagi, Poornima, Arora, Upasana, de Silva, Aravinda, Swaminathan, Sathyamangalam, Khanna, Navin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585145/
https://ncbi.nlm.nih.gov/pubmed/26441930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2015.01005
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