Virus-like particles derived from Pichia pastoris-expressed dengue virus type 1 glycoprotein elicit homotypic virus-neutralizing envelope domain III-directed antibodies

BACKGROUND: Four antigenically distinct serotypes (1–4) of dengue viruses (DENVs) cause dengue disease. Antibodies to any one DENV serotype have the potential to predispose an individual to more severe disease upon infection with a different DENV serotype. A dengue vaccine must elicit homotypic neut...

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Dettagli Bibliografici
Pubblicato in:BMC Biotechnol
Autori principali: Poddar, Ankur, Ramasamy, Viswanathan, Shukla, Rahul, Rajpoot, Ravi Kant, Arora, Upasana, Jain, Swatantra K., Swaminathan, Sathyamangalam, Khanna, Navin
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908714/
https://ncbi.nlm.nih.gov/pubmed/27301568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-016-0280-y
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