Virus-like particles derived from Pichia pastoris-expressed dengue virus type 1 glycoprotein elicit homotypic virus-neutralizing envelope domain III-directed antibodies

BACKGROUND: Four antigenically distinct serotypes (1–4) of dengue viruses (DENVs) cause dengue disease. Antibodies to any one DENV serotype have the potential to predispose an individual to more severe disease upon infection with a different DENV serotype. A dengue vaccine must elicit homotypic neut...

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Detalhes bibliográficos
Publicado no:BMC Biotechnol
Main Authors: Poddar, Ankur, Ramasamy, Viswanathan, Shukla, Rahul, Rajpoot, Ravi Kant, Arora, Upasana, Jain, Swatantra K., Swaminathan, Sathyamangalam, Khanna, Navin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908714/
https://ncbi.nlm.nih.gov/pubmed/27301568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-016-0280-y
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