Pichia pastoris-Expressed Dengue 2 Envelope Forms Virus-Like Particles without Pre-Membrane Protein and Induces High Titer Neutralizing Antibodies

Dengue is a mosquito-borne viral disease with a global prevalence. It is caused by four closely-related dengue viruses (DENVs 1–4). A dengue vaccine that can protect against all four viruses is an unmet public health need. Live attenuated vaccine development efforts have encountered unexpected inter...

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Autors principals: Mani, Shailendra, Tripathi, Lav, Raut, Rajendra, Tyagi, Poornima, Arora, Upasana, Barman, Tarani, Sood, Ruchi, Galav, Alka, Wahala, Wahala, de Silva, Aravinda, Swaminathan, Sathyamangalam, Khanna, Navin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662778/
https://ncbi.nlm.nih.gov/pubmed/23717637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064595
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