Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, attenuates postoperative cognitive dysfunction in aging mice

Postoperative cognitive dysfunction (POCD) is a recognized clinical entity characterized with cognitive deficits after anesthesia and surgery, especially in aged patients. Previous studies have shown that histone acetylation plays a key role in hippocampal synaptic plasticity and memory formation. H...

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Pubblicato in:Front Mol Neurosci
Autori principali: Jia, Min, Liu, Wen-Xue, Sun, He-Liang, Chang, Yan-Qing, Yang, Jiao-Jiao, Ji, Mu-Huo, Yang, Jian-Jun, Feng, Chen-Zhuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2015
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585136/
https://ncbi.nlm.nih.gov/pubmed/26441515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2015.00052
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