The histone deacetylase inhibitor suberoylanilide hydroxamic acid attenuates human astrocyte neurotoxicity induced by interferon-γ

BACKGROUNDS: Increasing evidence shows that the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) possesses potent anti-inflammatory and immunomodulatory properties. It is tempting to evaluate the potential of SAHA as a therapeutic agent in various neuroinflammatory and neurodegen...

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Bibliographic Details
Main Authors: Klegeris, Andis, McGeer, Patrick L
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410763/
https://ncbi.nlm.nih.gov/pubmed/22647614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-113
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