PTEN loss is a context‐dependent outcome determinant in obese and non‐obese endometrioid endometrial cancer patients

Endometrial cancer incidence is increasing, due in part to a strong association with obesity. Mutations in the phosphatidylinositol 3‐kinase (PI3K) pathway, the central relay pathway of insulin signals, occur in the majority of endometrioid adenocarcinomas, the most common form of endometrial cancer...

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Dades bibliogràfiques
Publicat a:Mol Oncol
Autors principals: Westin, Shannon N., Ju, Zhenlin, Broaddus, Russell R., Krakstad, Camilla, Li, Jane, Pal, Navdeep, Lu, Karen H., Coleman, Robert L., Hennessy, Bryan T., Klempner, Samuel J., Werner, Henrica M.J., Salvesen, Helga B., Cantley, Lewis C., Mills, Gordon B., Myers, Andrea P.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2015
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4584169/
https://ncbi.nlm.nih.gov/pubmed/26045339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.04.014
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