PTEN loss is a context‐dependent outcome determinant in obese and non‐obese endometrioid endometrial cancer patients

Endometrial cancer incidence is increasing, due in part to a strong association with obesity. Mutations in the phosphatidylinositol 3‐kinase (PI3K) pathway, the central relay pathway of insulin signals, occur in the majority of endometrioid adenocarcinomas, the most common form of endometrial cancer...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Oncol
Päätekijät: Westin, Shannon N., Ju, Zhenlin, Broaddus, Russell R., Krakstad, Camilla, Li, Jane, Pal, Navdeep, Lu, Karen H., Coleman, Robert L., Hennessy, Bryan T., Klempner, Samuel J., Werner, Henrica M.J., Salvesen, Helga B., Cantley, Lewis C., Mills, Gordon B., Myers, Andrea P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2015
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4584169/
https://ncbi.nlm.nih.gov/pubmed/26045339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.04.014
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