PTEN loss is a context‐dependent outcome determinant in obese and non‐obese endometrioid endometrial cancer patients

Endometrial cancer incidence is increasing, due in part to a strong association with obesity. Mutations in the phosphatidylinositol 3‐kinase (PI3K) pathway, the central relay pathway of insulin signals, occur in the majority of endometrioid adenocarcinomas, the most common form of endometrial cancer...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Westin, Shannon N., Ju, Zhenlin, Broaddus, Russell R., Krakstad, Camilla, Li, Jane, Pal, Navdeep, Lu, Karen H., Coleman, Robert L., Hennessy, Bryan T., Klempner, Samuel J., Werner, Henrica M.J., Salvesen, Helga B., Cantley, Lewis C., Mills, Gordon B., Myers, Andrea P.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4584169/
https://ncbi.nlm.nih.gov/pubmed/26045339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.04.014
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