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Proteomic profiling of endometrioid endometrial cancer reveals differential expression of hormone receptors and MAPK signaling proteins in obese versus non-obese patients

Endometrial cancer development is strongly linked to obesity, but knowledge regarding the influence of excess weight on endometrial tumor signaling pathways remains scarce. We therefore analyzed reverse phase protein array (RPPA) data for obesity-related protein expression patterns, using one traini...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Mauland, Karen Klepsland, Ju, Zhenlin, Tangen, Ingvild Løberg, Berg, Anna, Kalland, Karl-Henning, Øyan, Anne Margrete, Bjørge, Line, Westin, Shannon N., Krakstad, Camilla, Trovik, Jone, Mills, Gordon B., Hoivik, Erling A., Johanna Werner, Henrica Maria
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739790/
https://ncbi.nlm.nih.gov/pubmed/29291005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22203
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